Omeprazole is a cell-permeable, selective proton pump inhibitor. Omeprazole undergoes an acid-catalyzed rearrangement to a thiol-reactive cationic sulfenamide that inhibits (H+-K+)-ATPase in the gastric milieu. Omeprazole also acts as an aryl hydrocarbon-like inducer of cytochrome P450 secretion in human liver. This compound is an inhibitor a variety of CYP isoenzymes, including CYP2C19, CYP2C9 and CYP3A.
Omeprazole Base
| Description | |
|---|---|
| 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole | |
| 73590-58-6 | |
| C17H19N3O3S | |
| miol;elgam;zimor;ANTRA;LOSEC;aulcer;prysma;ulcsep;MEPRAL;ZOLTUM | |
| A selective proton pump and CYP inhibitor | |
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