Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT.
Fluoxetine HCL
Description | |
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N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine | |
59333-67-4 | |
C17H19ClF3NO | |
Zepax;LY-110;PROZAC;SARAFEM;Alzac 20;Deproxin;DigassiM;PROZAC(R);LY-110140;Affectine | |
Anti Depressant |