Daunorubicine HCL Product Enquiry

Daunorubicin hydrochloride is a DNA intercalating anthracylcine natural product isolated from Streptomyces peucetius. Upon intercalation, Daunorubicin forms stable complexes with the DNA backbone, inhibiting normal functioning of the double helix and the proteins that interact with it. Daunorubicin is nearly identical in structure to Doxorubicin (sc-200923), with Doxorubicin containing a pendant hydroxyl group on the exocyclic ketone. The action of Daunorubicin has been correlated to efficacy in suppressing the proliferation of certain acute leukemias. Daunorubicin hydrochloride is an inhibitor of Topo I and Topo II and an activator of LASS.

Chemical Name:

Daunorubicine HCL


Description
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
20830-81-3
C27H30ClNO10
ondena;Cerubidine;ndc0082-4155;daunoblastin;daunoblastina;DAUNOBLASTINE;DAUNOMYCIN HCL;DAUNOMYCINE HCL;DAUNORUBICIN HCL;WP900 HYDROCHLORIDE
Oncology
Note :
API/Substances covered by patents are not offered to the countries where valid Patent Law is in force. However, the final responsibility lies with the customer.
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